Prebiotic effects of NUTRIOSE®: a review (ICN Bangkok)
Berard M, Deremaux L, Lefranc-Millot C and Macioce V.
Prebiotic effects of NUTRIOSE®: a review.
International Congress of Nutrition – 4-9 October 2009, Bangkok, Thailand.
Increasing evidence suggests that gut microbiota is associated with gut health and general well-being. Some ingredients can modulate the colonic flora: it is
the case of some soluble dietary fibres which are poorly hydrolysed or absorbed in the upper part of the gastrointestinal tract, and induce a selective fermentation
in the colon in such a way that the composition of the intestinal microbiota is altered towards a healthier composition.
NUTRIOSE® is a dextrin containing about 85% soluble fibres. Animal and humans studies have demonstrated that deep changes occur in the colonic environment
during its digestion (1, 2, 3). The dextrin induces a large production of Short Chain Fatty Acids (SCFAs), mainly propionate, resulting in a decrease in the
colonic pH. Consequently, these fermentations benefit the colonocytes in the digestive epithelium and lead to an increased fecal concentration of alpha- and
beta-glucosidases by encouraging an increase in beneficial glucidolytic flora and a decrease in potentially pathogenic flora.
The aim of this review is to focus on the effects of NUTRIOSE® on the modulation of the gut microflora in humans.